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Home Antibody All anti-XRCC1 antibodies

Anti-XRCC1 CONJUGATED Antibody Clone OTI2D8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500886DM XRCC1 mouse monoclonal antibody, clone 2D8, DyLight 488 conjugated 100ul $600 In Stock
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Also for XRCC1 (NM_006297)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
Clone NameClone OTI2D8 IsotypeIgG1
Species ReactivityHuman Concentration0.57 mg/ml
Guaranteed Application * Suggested Dilutions
Predicted MW Explanation 69.3 kDa
Buffer
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens X-ray repair cross complementing 1 (XRCC1)
Alternative NameRCC; RCC
Database LinkNP_006288
FunctionThe protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq].
Related PathwayDruggable Genome Base excision repair

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