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Home Antibody All anti-XRCC1 antibodies

Anti-XRCC1 TRUEMAB Antibody clone 2D8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500886
  • XRCC1 mouse monoclonal antibody, clone 2D8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401897) , 20ug Explanation
100ul
30ul
325 In Stock
CF500886
  • Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone 2D8
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IHC(6)
FC(2)
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Also for XRCC1 (NM_006297)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
Clone Nameclone 2D8 IsotypeIgG1
Species ReactivityHuman Concentration0.57 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:2000, IHC 1:50, FLOW 1:100,
Predicted MW Explanation 69.3 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)
Alternative NameRCC
Database LinkNP_006288
Entrez Gene 7515 Human
FunctionThe protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq].
Related PathwayDruggable Genome Base excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (RC204952, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.
WB Image
Western blot analysis of extracts (10ug) from 4 different cell lines by using anti-XRCC1 monoclonal antibody at 1:200 dilution.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
FC Image
HEK293T cells transfected with either RC204952 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-XRCC1 antibody(TA500886), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-XRCC1 antibody(TA500886),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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