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Home Antibody All anti-XRCC1 antibodies

Anti-XRCC1 TRUEMAB Antibody Clone OTI2D8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA500886 XRCC1 mouse monoclonal antibody, clone OTI2D8 (formerly 2D8) 100ul
30ul
$325 In Stock
LC401897 XRCC1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500886 Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone OTI2D8 (formerly 2D8) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(6)
FC(2)
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Also for XRCC1 (NM_006297)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
Clone NameClone OTI2D8 IsotypeIgG1
Species ReactivityHuman Concentration0.57 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:2000, IHC 1:50, FLOW 1:100,
Predicted MW Explanation 69.3 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)
Alternative NameRCC
Database LinkNP_006288
Entrez Gene 7515 Human
FunctionThe protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq].
Related PathwayDruggable Genome Base excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (RC204952, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.
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Western blot analysis of extracts (10ug) from 4 different cell lines by using anti-XRCC1 monoclonal antibody at 1:200 dilution.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-XRCC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500886)
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HEK293T cells transfected with either RC204952 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-XRCC1 antibody(TA500886), and then analyzed by flow cytometry.
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Flow cytometric Analysis of Jurkat cells, using anti-XRCC1 antibody(TA500886),(Red), compared to a nonspecific negative control antibody,(Blue).
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