Anti-LOX Antibody, Clone 6B7

Also for LOX (NM_002317)

OriGene Data

Immunogen	Human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
Clone Name	Clone 6B7	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF, FC	Suggested Dilutions	WB 1:1000, IHC 1:50, IF 1:100, FLOW 1:100,
Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens lysyl oxidase (LOX), transcript variant 1
Alternative Name	MGC105112
Database Link	NP_002308
Function	The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LOX (RC213323, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LOX.

IHC Image

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-LOX mouse monoclonal antibody. (TA500869)

IHC Image

Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-LOX mouse monoclonal antibody. (TA500869)

IF Image

Anti-LOX mouse monoclonal antibody (TA500869) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX(RC213323).

FC Image

HEK293T cells transfected with either RC213323 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-LOX antibody(TA500869), and then analyzed by flow cytometry.

FC Image

Flow cytometric Analysis of Hela cells, using anti-LOX antibody(TA500869),(Red), compared to a nonspecific negative control antibody,(Blue).

FC Image

Flow cytometric Analysis of Jurkat cells, using anti-LOX antibody(TA500869),(Red), compared to a nonspecific negative control antibody,(Blue).

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-LOX TrueMAB Antibody Clone 6B7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data