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Home Antibody All anti-LOX antibodies

Anti-LOX TRUEMAB Antibody Clone OTI4E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500865 LOX mouse monoclonal antibody, clone OTI4E3 (formerly 4E3) 100ul $325 In Stock
LC400843 LOX HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500865 Carrier-free (BSA/glycerol-free) LOX mouse monoclonal antibody, clone OTI4E3 (formerly 4E3) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(1)
IF(1)
FC(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
Clone NameClone OTI4E3 IsotypeIgG1
Species ReactivityHuman Concentration0.42 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500, IHC 1:50, IF 1:100, FLOW 1:100,
Predicted MW Explanation 46.8 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens lysyl oxidase (LOX), transcript variant 1
Alternative NameMGC105112
Database LinkNP_002308
Entrez Gene 4015 Human
FunctionThe protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LOX (RC213323, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LOX.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500865)
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Anti-LOX mouse monoclonal antibody (TA500865) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX(RC213323).
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HEK293T cells transfected with either RC213323 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-LOX antibody(TA500865), and then analyzed by flow cytometry.
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