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Home Antibody All anti-LOX antibodies

Anti-LOX TRUEMAB Antibody Clone 3C3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500860
  • LOX mouse monoclonal antibody, clone 3C3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400843) , 20ug
100ul $325 In Stock
CF500860
  • Carrier-free (BSA/glycerol-free) LOX mouse monoclonal antibody, clone 3C3
100ug $450 8-10 Days
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WB(1)
IF(1)
FC(3)
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Also for LOX (NM_002317)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
Clone NameClone 3C3 IsotypeIgG1
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens lysyl oxidase (LOX), transcript variant 1
Alternative NameMGC105112
Database LinkNP_002308
FunctionThe protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LOX (RC213323, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LOX.
IF Image
Anti-LOX mouse monoclonal antibody (TA500860) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX(RC213323).
FC Image
HEK293T cells transfected with either RC213323 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-LOX antibody(TA500860), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Hela cells, using anti-LOX antibody(TA500860),(Red), compared to a nonspecific negative control antibody,(Blue).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-LOX antibody(TA500860),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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