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Anti-XRCC1 TRUEMAB Antibody clone 3C3
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for XRCC1 (NM_006297)
|Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.|
||WB 1:2000, IF 1:100,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1)|
Entrez Gene 7515 Human
|The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
|Druggable Genome Base excision repair|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC1 (RC204952, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC1.
Anti-XRCC1 mouse monoclonal antibody (TA500847) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY XRCC1(RC204952).