Home Antibody All anti-BIRC7 antibodies
Anti-BIRC7 TRUEMAB Antibody Clone OTI1D12
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for BIRC7 (NM_139317)
|Full length human recombinant protein of human BIRC7 (NP_071444) produced in HEK293T cell.|
|WB, IHC, FC
||WB 1:1000, IHC 1:50, Flow 1:100
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens baculoviral IAP repeat containing 7 (BIRC7), transcript variant 1|
|KIAP; LIVIN; ML-IAP; MLIAP; RNF50|
Entrez Gene 79444 Human
|The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.|
|Druggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIRC7 (RC204906, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC7.
Western blot analysis of extracts (10ug) from 10 Human tissue by using anti-BIRC7 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon;10: spleen).
Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-BIRC7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500758, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-BIRC7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500758, Dilution 1:50)
Flow cytometric analysis of Hela cells, using anti-BIRC7 antibody(TA500758),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).
Flow cytometric analysis of Jurkat cells, using anti-BIRC7 antibody(TA500758),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).