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Home Antibody All anti-PSMA7 antibodies

Anti-PSMA7 TRUEMAB Antibody Clone OTI3F11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500691 anti-PSMA7 mouse monoclonal antibody, clone OTI3F11 (formerly 3F11) 100ul $325 In Stock
LC400987 PSMA7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500691 Carrier-free (BSA/glycerol-free) PSMA7 mouse monoclonal antibody, clone OTI3F11 (formerly 3F11) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(7)
FC(1)
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Also for PSMA7 (NM_002792)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PSMA7 (NP_002783) produced in HEK293T cell.
Clone NameClone OTI3F11 IsotypeIgG1
Species ReactivityHuman Concentration0.66 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:2000, IHC 1:50, Flow 1:100
Predicted MW Explanation 27.9 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7)
Alternative NameC6; HSPC; RC6-1; XAPC7
Database LinkNP_002783
Entrez Gene 5688 Human
FunctionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9.
Related PathwayProteaseDruggable Genome Proteasome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMA7 (RC201169, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMA7.
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Immunohistochemical staining of paraffin-embedded colon tissue within the normal limits using anti-PSMA7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500691, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-PSMA7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500691, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-PSMA7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500691, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Ovary tissue within the normal limits using anti-PSMA7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500691, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded thyroid tissue within the normal limits using anti-PSMA7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500691, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded endometrium tissue within the normal limits using anti-PSMA7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500691, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded prostate tissue within the normal limits using anti-PSMA7mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500691, Dilution 1:50)
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HEK293T cells transfected with either pCMV6-ENTRY PSMA7(RC201169)(Red) or empty vector control plasmid(Blue) were immunostained with anti-PSMA7 mouse monoclonal(TA500691, Dilution 1:1,000), and then analyzed by flow cytometry.
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