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Home Antibody All anti-HSD17B10 antibodies

Anti-HSD17B10 TRUEMAB Antibody clone 3B5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500687
  • anti-HSD17B10 mouse monoclonal antibody, clone 3B5
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401426) , 20ug Explanation
100ul 325 In Stock
CF500687
  • Carrier-free (BSA/glycerol-free) HSD17B10 mouse monoclonal antibody, clone 3B5
100ug $450 3-4 weeks
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WB(1)
IHC(1)
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Also for HSD17B10 (NM_004493)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human HSD17B10 expression vector
Clone Nameclone 3B5 IsotypeIgG1
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:2000,
Predicted MW Explanation 26.9 KDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Reference Data

Target NameHomo sapiens hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), transcript variant 1
Alternative Name17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD;
Database LinkNP_004484
Entrez Gene 3028 Human
FunctionThis gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Related PathwayDruggable Genome Valine, leucine and isoleucine degradationMetabolic pathwaysAlzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSD17B10 (RC201734, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HSD17B10 .
IHC Image
Immunohistochemical staining of paraffin-embedded liver tissue using anti-HSD17B10 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500687, Dilution 1:50)

 

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