Anti-HSD17B10 Antibody, clone 10B4

Also for HSD17B10 (NM_004493)

OriGene Data

Immunogen	Full length human recombinant protein of human HSD17B10(NP_004484) produced in HEK293T cell.
Clone Name	clone 10B4	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF, FC	Suggested Dilutions	WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100
Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), nuclear gene encoding mitochondrial protein, transcript variant 1
Alternative Name	17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD;
Database Link	NP_004484
Function	This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Related Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSD17B10 (RC201734, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HSD17B10.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HSD17B10 monoclonal antibody.

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-HSD17B10mouse monoclonal antibody. (TA500686, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-HSD17B10mouse monoclonal antibody. (TA500686, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded liver tissue using anti-HSD17B10mouse monoclonal antibody. (TA500686, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-HSD17B10mouse monoclonal antibody. (TA500686, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-HSD17B10mouse monoclonal antibody. (TA500686, Dilution 1:50)

IF Image

Anti-HSD17B10 mouse monoclonal antibody (TA500686) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSD17B10(RC201734).

FC Image

Flow cytometric analysis of Hela cells, using anti-HSD17B10 antibody(TA500686),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).

FC Image

Flow cytometric analysis of Jurkat cells, using anti-HSD17B10 antibody(TA500686),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).

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Anti-HSD17B10 TrueMAB Antibody clone 10B4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data