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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-XRCC4 antibodies

Anti-XRCC4 TrueMAB Antibody clone 4H9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA500650
  • Purified anti-XRCC4 mouse monoclonal antibody, clone 4H9
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402930) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF500650
  • Carrier-free (BSA/glycerol-free) XRCC4 mouse monoclonal antibody, clone 4H9
100ug $450 3-4 weeks Add to Shopping Cart
WB(1)
IHC(13)
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Also for XRCC4 (NM_022550)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 3
Synonyms:DNA repair protein XRCC4; X-ray repair cross complementing protein 4; X-ray repair, complementing defective, repair in Chinese hamster; X-ray repair complementing defective repair in Chinese hamster cells 4
ImmunogenProtein expressed in 293T cell transfected with human XRCC4 expression vector
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 4H9 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:2000, IHC 1:50,
BackgroundThe protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY XRCC4 (RC218029, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-XRCC4.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-XRCC4 mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded colon tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded lung tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded thyroid tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of endometrium tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-XRCC4mouse monoclonal antibody. (TA500650, Dilution 1:50)

 

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