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Anti-SLC7A8 TRUEMAB Antibody Clone OTI2D4
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for SLC7A8 (NM_012244)
|Full length human recombinant protein of human SLC7A8 (NP_036376) produced in HEK293T cell.|
||IF 1:100, FLOW 1:100,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8), transcript variant 1|
Entrez Gene 23428 Human
|Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine orD,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.|
|TransmembraneDruggable Genome |
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Anti-SLC7A8 mouse monoclonal antibody (TA500631) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SLC7A8(RC208586).
HEK293T cells transfected with either RC208586 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SLC7A8 antibody(TA500631), and then analyzed by flow cytometry.