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Home Antibody All anti-PCSK7 antibodies

Anti-PCSK7 TRUEMAB Antibody Clone OTI1B8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA500628 PCSK7 mouse monoclonal antibody, clone OTI1B8 (formerly 1B8) 100ul $379 In Stock
CF500628 Carrier-free (BSA/glycerol-free) PCSK7 mouse monoclonal antibody, clone OTI1B8 (formerly 1B8) 100ug $450 3-4 weeks
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IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human PCSK7 (NP_004707) produced in HEK293T cell.
Clone NameClone OTI1B8 IsotypeIgG2a
Species ReactivityHuman Concentration0.89 mg/ml
Guaranteed Application *IF, FC Suggested DilutionsIF 1:100, FLOW 1:100,
Predicted MW Explanation 86.2 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens proprotein convertase subtilisin/kexin type 7 (PCSK7)
Alternative NameLPC; PC7; PC8; SPC7
Database LinkNP_004707
Entrez Gene 9159 Human
FunctionThe protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart.
Related PathwayTransmembraneProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Anti-PCSK7 mouse monoclonal antibody (TA500628) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PCSK7(RC203896).
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HEK293T cells transfected with either RC203896 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PCSK7 antibody(TA500628), and then analyzed by flow cytometry.
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