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Anti-ALDH2 TRUEMAB Antibody clone 4H2
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for ALDH2 (NM_000690)
|Full length human recombinant protein of human ALDH2 (NP_000681) produced in HEK293T cell.|
||IF 1:50~100, FLOW 1:100,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), transcript variant 1|
|ALDH-E2; ALDHI; ALDM|
|This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
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Anti-ALDH2 mouse monoclonal antibody (TA500615) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ALDH2(RC200505).
Immunofluorescent staining of HepG2 cells using anti-ALDH2 mouse monoclonal antibody (TA500615).
HEK293T cells transfected with either RC200505 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-ALDH2 antibody(TA500615), and then analyzed by flow cytometry.