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Anti-STAT1 TRUEMAB Antibody Clone OTI15H3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500566 anti-STAT1 mouse monoclonal antibody, clone OTI15H3 (formerly 15H3) 100ul $325 In Stock
LC408329 STAT1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500566 Carrier-free (BSA/glycerol-free) STAT1 mouse monoclonal antibody, clone OTI15H3 (formerly 15H3) 100ug $450 3-4 weeks
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WB(1)
IHC(4)
IF(1)
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Also for STAT1 (NM_139266)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human STAT1 expression vector
Clone NameClone OTI15H3 IsotypeIgG1
Species ReactivityHuman Concentration0.6 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:2000 IHC 1:50 IF 1:100
Predicted MW Explanation 91 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant beta
Alternative NameCANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Database LinkNP_644671
Entrez Gene 6772 Human
FunctionThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Related PathwayTranscription FactorsDruggable Genome Chemokine signaling pathwayToll-like receptor signaling pathwayJak-STAT signaling pathwayPathways in cancerPancreatic cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STAT1 (RC201075, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STAT1.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-STAT1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500566, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Carcinoma of pancreas tissue using anti-STAT1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500566, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-STAT1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500566, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Carcinoma of bladder tissue using anti-STAT1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500566, Dilution 1:50)
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Anti-STAT1 mouse monoclonal antibody (TA500566) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY STAT1(RC201075).
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