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Anti-AURKC TRUEMAB Antibody Clone OTI4F7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500553 anti-AURKC mouse monoclonal antibody, clone OTI4F7 (formerly 4F7) 100ul 325
In Stock
LC423127 AURKC HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500553 Carrier-free (BSA/glycerol-free) AURKC mouse monoclonal antibody, clone OTI4F7 (formerly 4F7) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human AURKC expression vector
Clone NameClone OTI4F7 IsotypeIgG1
Species ReactivityHuman Concentration0.84 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:500
Predicted MW Explanation 35.6 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens aurora kinase C (AURKC), transcript variant 1
Alternative NameAIE2; AIK3; ARK3; AurC; aurora-C; SPGF5; STK13
Database LinkNP_001015878
Entrez Gene 6795 Human
FunctionThis gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AURKC (RC213890, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AURKC.

WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-AURKC monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).(1:200)


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