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Home Antibody All anti-SOD1 antibodies

Anti-SOD1 TRUEMAB Antibody Clone OTI8B10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (1) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500495 SOD1 (Superoxide Dismutase 1) mouse monoclonal antibody, clone OTI8B10 (formerly 8B10) 100ul $379 In Stock
LC400160 SOD1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500495 Carrier-free (BSA/glycerol-free) SOD1 mouse monoclonal antibody, clone OTI8B10 (formerly 8B10) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(3)
FC(1)
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OriGene Data

ImmunogenFull length human recombinant protein of human SOD1 (NP_000445) produced in HEK293T cell.
Clone NameClone OTI8B10 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:1000~2000, IHC 1:50, FLOW 1:100,
Predicted MW Explanation 15.8 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens superoxide dismutase 1, soluble (SOD1)
Alternative NameALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD
Database LinkNP_000445
Entrez Gene 6647 Human
FunctionThe protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Amyotrophic lateral sclerosis (ALS)Huntington's diseasePrion diseases

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SOD1 (RC200725, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SOD1.
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WB Image
Western blot analysis of extracts (35ug) from 6 different cell lines by using anti-SOD1 monoclonal antibody (HepG2: human; HeLa: human; HT29: human; SVT2: mouse; A549: human; MCF7: human).
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IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-SOD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500495)
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IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SOD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500495)
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IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SOD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500495)
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FC Image
HEK293T cells transfected with either RC200725 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SOD1 antibody(TA500495), and then analyzed by flow cytometry.
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