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Anti-HSP90AB1 TrueMAB Antibody clone 4C10
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for HSP90AB1 (NM_007355)
|Protein expressed in 293T cell transfected with human HSP90AB1 expression vector|
|Human, Dog, Rat, Monkey
||0.5~1.0 mg/ml (Lot Dependent)
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1), transcript variant 2|
|D6S182; HSP84; HSP90B; HSPC2; HSPCB|
|HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219)|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSP90AB1 (RC201070, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HSP90AB1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HSP90AB1 monoclonal antibody.