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Home Antibody All anti-BRAF antibodies

Anti-BRAF CONJUGATED Antibody clone 5A9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500431HM
  • BRAF mouse monoclonal antibody, clone 5A9, PE conjugated
100ul 600 1-2 Weeks
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Also for BRAF (NM_004333)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human BRAF (NP_004324) produced in HEK293T cell.
Clone Nameclone 5A9 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.5mg/ml
Guaranteed Application * Suggested Dilutions
Buffer
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens v-raf murine sarcoma viral oncogene homolog B (BRAF)
Alternative NameB-RAF1; BRAF1; NS7; RAFB1
Database LinkNP_004324
FunctionThis gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases.This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation,and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma,non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Related Pathway
Focal Adhesion
MAPK signaling pathway
Senescence and Autophagy

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