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Anti-TYRO3 TRUEMAB Antibody Clone OTI5B7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500415 TYRO3 mouse monoclonal antibody, clone OTI5B7 (formerly 5B7) 100ul
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CF500415 Carrier-free (BSA/glycerol-free) TYRO3 mouse monoclonal antibody, clone OTI5B7 (formerly 5B7) 100ug $450 3-4 weeks
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Also for TYRO3 (NM_006293)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TYRO3 (NP_006284) produced in HEK293T cell.
Clone NameClone OTI5B7 IsotypeIgG2a
Species ReactivityHuman Concentration1.34 mg/ml
Guaranteed Application *IF, IP, FC Suggested DilutionsIF 1:100, FLOW 1:100, IP 2ug/500ul
Predicted MW Explanation 96.7 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens TYRO3 protein tyrosine kinase (TYRO3)
Alternative NameBYK; Dtk; Etk-2; Rek; RSE; Sky; Tif
Database LinkNP_006284
Entrez Gene 7301 Human
FunctionThe gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Anti-TYRO3 mouse monoclonal antibody (TA500415) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TYRO3(RC208260).
Immunoprecipitation(IP) of TYRO3 by using TrueMab monoclonal anti-TYRO3 antibodies (Negative control: IP without adding anti-TYRO3 antibody.). For each experiment, 500ul of DDK tagged TYRO3 overexpression lysates (at 1:5 dilution with HEK293T lysate), 2ug of anti-TYRO3 antibody and 20ul (0.1mg) of goat anti-mouse conjugated magnetic beads were mixed and incubated overnight. After extensive wash to remove any non-specific binding, the immuno-precipitated products were analyzed with rabbit anti-DDK polyclonal antibody.
HEK293T cells transfected with either RC208260 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TYRO3 antibody(TA500415), and then analyzed by flow cytometry.


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