Anti-STK3 Antibody, clone 2D4

Also for STK3 (NM_006281)

OriGene Data

Immunogen	Protein expressed in 293T cell transfected with human STK3 expression vector
Clone Name	clone 2D4	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB 1:2000; IHC 1:50
Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens serine/threonine kinase 3 (STK3), transcript variant 1
Alternative Name	KRS1; MST2
Database Link	NP_006272
Function	Protein kinase activation is a frequent response of cells to treatment with growth factors,chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast ' sterile 20'(Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand
Related Pathway	MAPK signaling pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY STK3 (RC203897, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-STK3.

IHC Image

Immunohistochemical staining of paraffin-embedded breast tissue using anti-STK3 mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-STK3 mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded colon tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded lung tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Ovary tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded endometrium tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

IHC Image

Immunohistochemical staining of paraffin-embedded prostate tissue using anti-STK3mouse monoclonal antibody. (TA500409, Dilution 1:50)

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-STK3 TrueMAB Antibody clone 2D4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data