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Home Antibody All anti-TRPM4 antibodies

Anti-TRPM4 SMALL PACK Antibody Clone OTI10H5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500381S TRPM4 mouse monoclonal antibody, clone 10H5 30ul $120 In Stock
CF500381 Carrier-free (BSA/glycerol-free) TRPM4 mouse monoclonal antibody, clone OTI10H5 (formerly 10H5) 30ulug $450 4 Weeks
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Also for TRPM4 (NM_017636)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TRPM4 (NP_060106) produced in HEK293T cell.
Clone NameClone OTI10H5 IsotypeIgG1
Species ReactivityHuman , Dog , Monkey Concentration0.77 mg/ml
Guaranteed Application * Suggested Dilutions
Predicted MW Explanation 134.3 kDa
Buffer
Purification Purified from cell culture supernatant by affinity chromatography

Reference Data

Target NameHomo sapiens transient receptor potential cation channel subfamily M member 4 (TRPM4), transcript variant 1
Alternative NamehTRPM4; LTrpC4; PFHB1B; TRPM4B
Database LinkNP_060106
FunctionCalcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by increase in intracellular Ca(2+), it is impermeable to it. Mediates transport of monovalent cations (Na(+) > K(+) > Cs(+) > Li(+)), leading to depolarize the membrane. It thereby plays a central role in cadiomyocytes, neurons from entorhinal cortex, dorsal root and vomeronasal neurons, endocrine pancreas cells, kidney epithelial cells, cochlea hair cells etc. Participates in T-cell activation by modulating Ca(2+) oscillations after T lymphocyte activation, which is required for NFAT-dependent IL2 production. Involved in myogenic constriction of cerebral arteries. Controls insulin secretion in pancreatic beta-cells. May also be involved in pacemaking or could cause irregular electrical activity under conditions of Ca(2+) overload.
Related PathwayIon Channels: Transient receptor potentialTransmembraneDruggable Genome

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