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Home Antibody All anti-VEGF antibodies

Anti-VEGF TRUEMAB Antibody clone 4E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500289
  • VEGFA (VEGF) mouse monoclonal antibody, clone 4E3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC422435) , 20ug
100ul 325 In Stock
CF500289
  • Carrier-free (BSA/glycerol-free) VEGF mouse monoclonal antibody, clone 4E3
100ug $450 3-4 weeks
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WB(1)
IHC(4)
IF(1)
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Also for VEGF (NM_001025366)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 27-233 of human VEGFA (NP_003367) produced in E.coli.
Clone Nameclone 4E3 IsotypeIgG1
Species ReactivityHuman Concentration0.50 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:1000, IHC 1:50, IF 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 1
Alternative NameMVCD1; VEGF; VPF
Database LinkNP_001020537
FunctionVEGF is a member of the PDGF/VEGF growth factor family that is often found as a disulfide linked homodimer. It is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF gene have been associated with proliferative and nonproliferative diabetic retinopathy.
Related Pathway
Cytokine-cytokine receptor interaction
Focal Adhesion
Hemostasis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY VEGF (RC223789, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-VEGF.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-VEGF mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500289)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-VEGF mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500289)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-VEGF mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500289)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-VEGF mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500289)
IF Image
Anti-VEGF mouse monoclonal antibody (TA500289) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY VEGF(RC223789).

 

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