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Anti-TNNI3 TRUEMAB Antibody Clone OTI3G2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500255 anti-TNNI3 (Cardiac Troponin I) mouse monoclonal antibody, clone OTI3G2 (formerly 3G2) 100ul 325
In Stock
LC424766 TNNI3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500255 Carrier-free (BSA/glycerol-free) TNNI3 mouse monoclonal antibody, clone OTI3G2 (formerly 3G2) 100ug $450 3-4 weeks
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Also for TNNI3 (NM_000363)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant protein expressed in E.coli corresponding to amino acids 1-210 of human TNNI3
Clone NameClone OTI3G2 IsotypeIgG2a
Species ReactivityHuman Concentration0.9 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:2000 IHC 1:50
Predicted MW Explanation 32.7 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens troponin I type 3 (cardiac) (TNNI3)
Alternative NameCMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1
Database LinkNP_000354
Entrez Gene 7137 Human
FunctionTroponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM)
Related PathwayES Cell Differentiation/IPSStem cell - PluripotencyDruggable Genome Cardiac muscle contractionHypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNNI3 (RC214740, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNNI3.
Immunohistochemical staining of paraffin-embedded prostate tissue within the normal limits using anti-TNNI3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500255, Dilution 1:50)


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