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Home Antibody All anti-BCL2L1 antibodies

Anti-BCL2L1 CONJUGATED Antibody clone 4A9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500097S
  • anti-Bcl-XL mouse monoclonal antibody,clone 4A9
30ul 120 In Stock
CF500097
  • Carrier-free (BSA/glycerol-free) Bcl-XL mouse monoclonal antibody,clone 4A9
30ulug $450 3-4 weeks
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Also for BCL2L1 (NM_138578)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL
Clone Nameclone 4A9 IsotypeIgG2a
Species ReactivityHuman Concentration0.25mg/ml
Guaranteed Application * Suggested Dilutions
Buffer

Reference Data

Target NameHomo sapiens BCL2-like 1 (BCL2L1), transcript variant 1
Alternative NameBcl-X; bcl-xL; BCL-XL/S; bcl-xS; BCL2L; BCLX; BCLXL; BCLXS; PPP1R52
Database LinkNP_612815
FunctionBcl-XL belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator
Related Pathway
Apoptosis
Jak-STAT signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

 

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