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Anti-BCL2L1 TRUEMAB Antibody clone 4A9
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for BCL2L1 (NM_138578)
|Recombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL|
||WB: 1:500, IF (1:100)
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Homo sapiens BCL2-like 1 (BCL2L1), transcript variant 1|
|Bcl-X; bcl-xL; BCL-XL/S; bcl-xS; BCL2L; BCLX; BCLXL; BCLXS; PPP1R52|
Entrez Gene 598 Human
|Bcl-XL belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator|
|ES Cell Differentiation/IPSTransmembraneDruggable Genome ApoptosisJak-STAT signaling pathwayAmyotrophic lateral sclerosis (ALS)Pathways in cancerPancreatic cancerChronic myeloid leukemiaMore Pathways >> |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1(RC201314) (RC201314, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.
Anti-BCL2L1 mouse monoclonal antibody (TA500097) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY BCL2L1(RC201314).
Immunofluorescent staining of HT29 cells using anti-BCL2L1 mouse monoclonal antibody (TA500097).