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Home Antibody All anti-Notch1 antibodies

Anti-Notch1 CONJUGATED Antibody clone 3E12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500078S
  • anti-Notch1 mouse monoclonal antibody,clone 3E12
30ul $120 In Stock
CF500078
  • Carrier-free (BSA/glycerol-free) Notch1 mouse monoclonal antibody,clone 3E12
30ulug $450 3 Days
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Also for Notch1 (NM_017617)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein expressed in E.coli corresponding to amino acids 2300-2556 of human NOTCH1
Clone Nameclone 3E12 IsotypeIgG2b
Species ReactivityHuman Concentration0.43mg/ml
Guaranteed Application * Suggested Dilutions
Buffer
Purification Puridied form mouse ascites fluids

Reference Data

Target NameHomo sapiens notch 1 (NOTCH1)
Alternative NamehN1; TAN1
Database LinkNP_060087
FunctionNotch1 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development
Related Pathway
Delta-Notch Signaling Pathway

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