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Home Antibody All anti-SERPINA1 antibodies

Anti-SERPINA1 TRUEMAB Antibody Clone OTI3C5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500069 SERPINA1 mouse monoclonal antibody, clone OTI3C5 (formerly 3C5) 100ul $325 In Stock
LC400112 SERPINA1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500069 Carrier-free (BSA/glycerol-free) SERPINA1 mouse monoclonal antibody, clone OTI3C5 (formerly 3C5) 100ug $450 8-10 Days
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WB(2)
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Also for SERPINA1 (NM_000295)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 26-418 of human A1AT (NP_000286) produced in E.coli.
Clone NameClone OTI3C5 IsotypeIgG2b
Species ReactivityHuman Concentration0.44 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:1000~2000,
Predicted MW Explanation 46.6 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 1
Alternative NameA1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275
Database LinkNP_000286
Entrez Gene 5265 Human
FunctionA1AT is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in A1AT gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.
Related PathwaySecreted ProteinES Cell Differentiation/IPSDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINA1 (RC202082, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINA1.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SERPINA1 monoclonal antibody.
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