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Anti-VEGF TrueMAB Antibody clone 4G3
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for VEGF (NM_001025366)
|Human recombinant protein fragment corresponding to amino acids 27-233 of human VEGFA (NP_003367) produced in E.coli.|
|Human , Dog
||0.5~1.0 mg/ml (Lot Dependent)
||WB 1:2500~5000, IHC 1:50,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 1|
|MVCD1; VEGF; VPF|
|VEGF is a member of the PDGF/VEGF growth factor family that is often found as a disulfide linked homodimer. It is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF gene have been associated with proliferative and nonproliferative diabetic retinopathy.|
Cytokine-cytokine receptor interaction
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY VEGF (RC223789, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-VEGF.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-VEGF monoclonal antibody.
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-VEGF mouse monoclonal antibody. (TA500042)
Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-VEGF mouse monoclonal antibody. (TA500042)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-VEGF mouse monoclonal antibody. (TA500042)