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Home Antibody All anti-PDX1 antibodies

Anti-PDX1 TRUEMAB Antibody clone 2A12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500038
  • Pdx1 mouse monoclonal antibody, clone 2A12
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400074) , 20ug Explanation
100ul
30ul
325 In Stock
CF500038
  • Carrier-free (BSA/glycerol-free) Pdx1 mouse monoclonal antibody, clone 2A12
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IHC(2)
IF(2)
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Also for PDX1 (NM_000209)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Clone Nameclone 2A12 IsotypeIgG1
Species ReactivityHuman Concentration0.23 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:20000, IHC 1:50, IF 1:50~100,
Predicted MW Explanation 30.6 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens pancreatic and duodenal homeobox 1 (PDX1)
Alternative NameGSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
Database LinkNP_000200
Entrez Gene 3651 Human
FunctionPdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Related PathwayES Cell Differentiation/IPSEmbryonic stem cellsInduced pluripotent stem cellsTranscription Factors Type II diabetes mellitusMaturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDX1 (RC222354, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDX1.
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-PDX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500038)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PDX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500038)
IF Image
Anti-PDX1 mouse monoclonal antibody (TA500038) immunofluorescent staining of HELA cells transiently transfected by pCMV6-ENTRY PDX1(RC222354).
IF Image
Immunofluorescent staining of HT29 cells using anti-PDX1 mouse monoclonal antibody (TA500038).

 

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