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Home Antibody All anti-PDX1 antibodies

Anti-PDX1 TRUEMAB Antibody Clone OTI2A12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500038
  • Pdx1 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400074) , 20ug Explanation
100ul
30ul
$325 In Stock
CF500038
  • Carrier-free (BSA/glycerol-free) Pdx1 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12)
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(2)
IF(2)

OriGene Data

ImmunogenFull length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Clone NameClone OTI2A12 IsotypeIgG1
Species ReactivityHuman Concentration0.23 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:20000, IHC 1:50, IF 1:50~100,
Predicted MW Explanation 30.6 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens pancreatic and duodenal homeobox 1 (PDX1)
Alternative NameGSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1
Database LinkNP_000200
Entrez Gene 3651 Human
FunctionPdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Related PathwayES Cell Differentiation/IPSEmbryonic stem cellsInduced pluripotent stem cellsTranscription Factors Type II diabetes mellitusMaturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDX1 (RC222354, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDX1.
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PDX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500038)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PDX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500038)
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Anti-PDX1 mouse monoclonal antibody (TA500038) immunofluorescent staining of HELA cells transiently transfected by pCMV6-ENTRY PDX1(RC222354).
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Immunofluorescent staining of HT29 cells using anti-PDX1 mouse monoclonal antibody (TA500038).
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