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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-MYC antibodies

Anti-MYC TrueMAB Antibody clone 5G3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA500004
  • Purified c-Myc (c-Myc ) mouse monoclonal antibody, clone 5G3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400876) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF500004
  • Carrier-free (BSA/glycerol-free) c-Myc mouse monoclonal antibody, clone 5G3
100ug $450 3-4 weeks Add to Shopping Cart
WB(2)
IHC(9)
IF(1)
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Also for MYC (NM_002467)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)
Synonyms:bHLHe39; c-Myc; MRTL
ImmunogenFull length human recombinant protein of human Myc (NP_002458) produced in E.coli.
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 5G3 IsotypeIgG2b
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:50~100, IHC 1:50, IF 1:100,
Backgroundc-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Related Pathway
Apoptosis
Cell cycle
EGFR1 Signaling Pathway
Jak-STAT signaling pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MYC (RC201611, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MYC.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MYC monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-MYC mouse monoclonal antibody. (TA500004)
IF Image
Anti-MYC mouse monoclonal antibody (TA500004) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MYC(RC201611).

 

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