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[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
Homo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), transcript variant 1
Synonyms:
FEX; GPR49; GPR67; GRP49; HG38
Immunogen
Human recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in HEK293T cell.
Buffer
PBS containing 0.1% BSA and 0.05% Sodium Azide
Clone Name
2A2
Isotype
IgG1
Species Reactivity
Human , Mouse
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Purification
Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose) (Protein A or G Sepharose)
Guaranteed Application *
FC
Suggested Dilutions
FC
Background
LGR5 (leucine-rich repeat containing G protein-coupled receptor 5) An Orphan GPCR protein, contains large extracellular domain, Stem cell biomarker for small intestine, active in colon cancer; overexpressed in ovary and liver tumors.
Related Pathway
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HT29 cells are detached, fixed with 2% formaldehyde for 10 min, and permeabilized with 0.1% trixon-X100. After blocking, the cells are stained with Dylight633-conjugated mouse IgG1 (red line) or Dylight633-conjugated LGR5 antibodies (blue line).
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