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Home Antibody All anti-BIRC5 antibodies

Anti-BIRC5 CONJUGATED Antibody Clone OTI2D9


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SKU Description Amount Price Availability*  
TA400025 Anti-BIRC5/Survivin mouse mAb, clone OTI2D9, HRP conjugated 100 ul $325 In Stock
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Also for BIRC5 (NM_001168)
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OriGene Data

ImmunogenFull length human recombinant protein of human BIRC5 (NP_001159) produced in HEK293T cell.
Clone NameClone OTI2D9 IsotypeIgG1
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
Predicted MW Explanation 16.2 kDa
BufferPBS (pH7.4) containing 50% glycerol, 0.1% BSA and 0.02% NaN3
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 1
Alternative NameAPI4; EPR-1
Database LinkNP_001159
FunctionThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Related PathwayStem cell - PluripotencyDruggable Genome Pathways in cancerColorectal cancer

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with pCMV6-ENTRY control (Lane 1) or pCMV6-ENTRY BIRC5 (Lane 2) plasmids for 48 hrs. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC5- HRP.


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