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Home Antibody All anti-GRIN2A antibodies

Anti-GRIN2A Antibody Polyclonal

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SKU Description Amount Price Availability*  
TA350718 Rabbit Polyclonal Anti-GRIN2A Antibody 100ul $325 In Stock
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IHC(1)

OriGene Data

ImmunogenSynthetic peptide of human GRIN2A
Clone NamePolyclonal IsotypeIgG
Species ReactivityH,M,R Concentration2.2 mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 2000-5000, IHC: 25-100
BufferpH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens glutamate ionotropic receptor NMDA type subunit 2A (GRIN2A), transcript variant 2
Alternative NameEPND; FESD; GluN2A; LKS; NMDAR2A; NR2A
Database LinkNP_000824
FunctionThis gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
Related PathwayIon Channels: SodiumTransmembraneIon Channels: Glutamate ReceptorsIon Channels: Glutamate ReceptorsDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionLong-term potentiationAlzheimer's diseaseAmyotrophic lateral sclerosis (ALS)Systemic lupus erythematosusMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


IHC Image
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using (GRIN2A Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
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