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Home Antibody All anti-ARID1A antibodies

Anti-ARID1A Antibody Polyclonal


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SKU Description Amount Price Availability*  
TA349170 Rabbit Polyclonal Anti-ARID1A Antibody 0.1mg $325 3-7 Days
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OriGene Data

ImmunogenARID1A antibody was raised against an 18 amino acid peptide near the amino terminus of human ARID1A.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1 mg/mL
Guaranteed Application *WB Suggested DilutionsWB: 1 - 2 ug/mL
Predicted MW Explanation Predicted: 133, 227, 251 kDa Observed: 130, 260 kD
BufferPBS containing 0.02% sodium azide.
Purification ARID1A antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens AT-rich interaction domain 1A (ARID1A), transcript variant 1
Alternative NameB120; BAF250; BAF250a; BM029; C1orf4; ELD; hELD; hOSA1; MRD14; OSA1; P270; SMARCF1
Database LinkNP_006006
Entrez Gene 8289 Human
Entrez Gene 93760 Mouse
Entrez Gene 297867 Rat
Entrez Gene 0 Monkey
Entrez Gene 0 Dog
FunctionThe ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1). It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2).
Related PathwayDruggable Genome

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WB Image
Western blot analysis of ARID1A in SK-N-SH cell lysate with ARID1A antibody at (A) 1 and (B) 2 ug/mL.


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