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Home Antibody All anti-DYRK3 antibodies

Anti-DYRK3 Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA336574 Rabbit Polyclonal DYRK3 Antibody 0.1ml $325 3-7 days
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WB(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide made to an internal portion of human DYRK3 (within residues 500-600). [Swiss-Prot# O43781]
Clone Name Isotype
Species ReactivityHuman, Primate, Mouse (Negative), Rat (Negative) Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 2 ug/ml, IF: 1:50,
Predicted MW Explanation 65 kDa
BufferTris-citrate/phosphate, pH 7, 0.1% Sodium azide. Store at 4C. Do not freeze.
Purification Immunogen affinity purified
Note This DYRK3 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen ~65 kDa. In ICC/IF distinct nuclear staining along with general cytoplasmic staining was observed in Hela cells.

Reference Data

Target Namedual specificity tyrosine phosphorylation regulated kinase 3
Alternative NameDYRK5|RED|REDK|hYAK3-2
Database LinkNP_001004023
Entrez Gene 8444 Human
Entrez Gene 226419 Mouse
Entrez Gene 304775 Rat
Entrez Gene 0 Monkey
Entrez Gene 0 Dog
FunctionDYRK3, or dual specificity tyrosine-phosphorylation-regulated kinase 3, is a negative regulator of EPO-dependent erythropoiesis and may place an upper limit on red cell production during stress erythropoiesis. DYRK3 inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells, and may also act by regulating CREB/CRE signaling.
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western Blot: DYRK3 Antibody [TA336574] - Detection of DYRK3 in Jurkat nuclear extracts using TA336574.
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IF Image
Immunocytochemistry/Immunofluorescence: DYRK3 Antibody [TA336574] - DYRK3 antibody was tested in Hela cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).
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