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Home Antibody All anti-HGF antibodies

Anti-HGF Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA335252 Rabbit Polyclonal Anti-HGF Antibody 50ug $325 3-7 days
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WB(1)

OriGene Data

ImmunogenThe immunogen for anti-HGF antibody: synthetic peptide directed towards the middle region of human HGF. Synthetic peptide located within the following region: NENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNLDHPVI
Clone Name IsotypeIgG
Species ReactivityHuman, Rabbit, Bovine, Pig, Horse, Rat, Mouse, Dog ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB
Predicted MW Explanation 83 kDa
BufferShipped as lyophilized powder. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Purification Affinity Purified
Note Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 93%

Reference Data

Target Namehepatocyte growth factor
Alternative NameDFNB39|F-TCF|HGFB|HPTA|SF
Database LinkNP_001010932
Entrez Gene 3082 Human
Entrez Gene 15234 Mouse
Entrez Gene 24446 Rat
Entrez Gene 0 Monkey
Entrez Gene 403441 Dog
FunctionHepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.
Related PathwayES Cell Differentiation/IPSTransmembraneProteaseAdult stem cellsDruggable Genome Cytokine-cytokine receptor interactionFocal adhesionPathways in cancerRenal cell carcinomaMelanoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
WB Suggested Anti-HGF Antibody Titration: 0.2-1 ug/ml; Positive Control: ACHN cell lysate
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