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Home Antibody All anti-PDZD3 antibodies

Anti-PDZD3 Antibody

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA331733 Rabbit Polyclonal Anti-PDZD3 Antibody 50ug $325 3-7 days
LC403028 PDZD3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenThe immunogen for Anti-PDZD3 Antibody is: synthetic peptide directed towards the C-terminal region of Human PDZD3. Synthetic peptide located within the following region: APLAEGWALPTKPRCLHLEKGPQGFGFLLREEKGLDGRPGQFLWEVDPGL
Clone Name IsotypeIgG
Species ReactivityHuman, Dog, Pig, Bovine, Mouse, Rat, Horse, Rabbit ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB
Predicted MW Explanation 62kDa
BufferShipped as lyophilized powder. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Note Immunogen sequence homology: Human: 100%; Dog: 93%; Pig: 93%; Mouse: 93%; Bovine: 93%; Rat: 86%; Horse: 86%; Rabbit: 86%

Reference Data

Target NameHomo sapiens PDZ domain containing 3 (PDZD3), transcript variant 2
Alternative NameIKEPP; NHERF4; PDZK2
Database LinkNP_079067
Entrez Gene 79849 Human
Entrez Gene 170761 Mouse
Entrez Gene 500986 Rat
Entrez Gene 0 Monkey
Entrez Gene 610585 Dog
FunctionGuanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Host: Rabbit; Target Name: PDZD3; Sample Tissue: HepG2 Whole Cell lysates; Antibody Dilution: 1.0ug/ml
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