Home Antibody All anti-PFE antibodies
|Recombinant protein of human PTH1R|
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3|
|Homo sapiens parathyroid hormone 1 receptor (PTH1R), transcript variant 1|
|PFE; PTHR; PTHR1|
|The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansens metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. |
Signaling by GPCR
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Western blot analysis of extracts of various cell lines, using PTH1R antibody.