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Home Antibody All anti-JUP antibodies

Anti-JUP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326865
  • Rabbit anti-JUP Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400807) , 20ug Explanation
100ug 325 3 Weeks
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WB(1)
IHC(2)
IF(1)
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Also for JUP (NM_002230)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein of human JUP
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200
BufferStore at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Affinity purification

Reference Data

Target NameHomo sapiens junction plakoglobin (JUP), transcript variant 1
Alternative NameARVD12; CTNNG; DP3; DPIII; PDGB; PKGB
Database LinkNP_002221
Entrez Gene 3728 Human
Entrez Gene 16480 Mouse
Entrez Gene 81679 Rat
FunctionThis gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
Related PathwayDruggable Genome Pathways in cancerAcute myeloid leukemiaArrhythmogenic right ventricular cardiomyopathy (ARVC)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts of various cell lines, using JUP antibody.
IHC Image
Immunohistochemistry of paraffin-embedded human stomach cancer using JUP antibody at dilution of 1:200 (400x lens).
IHC Image
Immunohistochemistry of paraffin-embedded human esophageal cancer using JUP antibody at dilution of 1:200 (400x lens).
IF Image
Immunofluorescence analysis of HeLa cell using JUP antibody. Blue: DAPI for nuclear staining.

 

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