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Home Antibody All anti-JAK2 antibodies

Anti-JAK2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326831
  • Jak2 Rabbit Polyclonal Antibody
100ug 325 3 Weeks
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WB(1)
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Also for JAK2 (NM_004972)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide of human Jak2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; ICC: 1:50-1:200
BufferStore at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Affinity purification

Reference Data

Target NameHomo sapiens Janus kinase 2 (JAK2)
Alternative NameJTK10; THCYT3
Database LinkNP_004963
Entrez Gene 3717 Human
Entrez Gene 16452 Mouse
Entrez Gene 24514 Rat
FunctionMembers of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors. Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats , Shc, insulin receptor substrates, and focal adhesion kinase (FAK), typically contain SH2 or other phospho-tyrosine-binding domains.
Related PathwayProtein KinaseDruggable Genome Chemokine signaling pathwayJak-STAT signaling pathwayAdipocytokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts of various cell lines, using JAK2 antibody.

 

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