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Home Antibody All anti-Kcnb1 antibodies

Anti-Kcnb1 Antibody S4-11


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SKU Description Amount Price Availability*  
TA326553 Mouse Monoclonal Anti-Kv2.1 Antibody 100µg $325 3-7 Days
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OriGene Data

ImmunogenBacterially expressed GST Bacterially expressed GSTfusion protein corresponding to amino acids 509-853 of rat KV2.1,
Clone NameS4-11 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat, Monkey Concentration1mg/mL
Guaranteed Application *IHC Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol
Purification Protein G Purified
Note Detects ~105-125kDa. Recognizes the Shab related a- subunit Kv2.1.

Reference Data

Target NameRattus norvegicus potassium voltage-gated channel subfamily B member 1 (Kcnb1)
Alternative NameDRK1PC; Kcr1-1; Kv2.1; Shab
Database LinkNP_037318
Entrez Gene 3745 Human
Entrez Gene 16500 Mouse
Entrez Gene 25736 Rat
Entrez Gene 703520 Monkey
FunctionVoltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia .
Related Pathway

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IHC Image
IHC analysis of Kv2.1 tested on mouse brain hippocampus showing strong membrane staining of neurons, using a dilution of the antibody


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