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Home Antibody All anti-Kcna1 antibodies

Anti-Kcna1 Antibody S20-78


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SKU Description Amount Price Availability*  
TA326548 Mouse Monoclonal Anti-Kv1.1 Antibody 100µg $325 3-7 Days
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OriGene Data

ImmunogenSynthetic peptide amino acids 458-476 (cytoplasmic C-terminus) of rat Kv1.1 (EEDMNNSIAHYRQANIRTG)
Clone NameS20-78 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *IHC Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol
Purification Protein G Purified
Note ~85kDa (major: Mature glycosylation), ~65kDa (minor: immature glycosylation)

Reference Data

Target NameRattus norvegicus potassium voltage-gated channel subfamily A member 1 (Kcna1)
Alternative NameKcna; Kcpvd; Kv1.1
Database LinkNP_775118
Entrez Gene 3736 Human
Entrez Gene 16485 Mouse
Entrez Gene 24520 Rat
FunctionKv1.1, also known as potassium voltage-gated channel subfamily A member 1, is a shaker related voltage potassium channel that in humans is encoded by the SCNA1 gene . It is strongly expressed in a variety of neurons in adult rodents, and it appears to be involved in regulating neuronal excitability. Specifically it plays a role in several developmental processes including proliferation, migration and cell-cell adhesion . The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel .
Related Pathway

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IHC Image
IHC analysis of Kv1.1 using the antibody


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