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Anti-KCNMB4 TRUEMAB Antibody S18A-3
Also for KCNMB4 (NM_014505)
|Fusion protein amino acids 45-167 (entire extracellular domain) of mouse BKBeta4, |
|Human, Mouse, Rat.
||WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
|PBS pH7.4, 50% glycerol, 0.09% sodium azide |
|Protein G Purified
|Homo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 4 (KCNMB4)|
|calcium-activated potassium channel beta 4 subunit; large conductance calcium-dependent potassium ion channel beta 4 subunit; potassium large conductance calcium-activated channel, subfamily M, beta member 4|
|BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release . A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia . This has major implications on other physiological processes in tissues other than the brain.|
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IHC of BK Beta4 in brain tissues using a dilution of the antibody