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Home Antibody All anti-KCNMB2 antibodies

Anti-KCNMB2 Antibody S53-32

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326488
  • Mouse Monoclonal Anti-BK Beta2 Antibody
100µg $325 3-7 Days
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WB(1)
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Also for KCNMB2 (NM_181361)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenFusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 (
Clone NameS53-32 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects endogenous and exogenous hsp22 in monomeric, dimeric and tetrameric forms in WB. Does not cross react with alpha crystallin.

Reference Data

Target NameHomo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2), transcript variant 1
Alternative NameMGC22431
Database LinkNP_852006
FunctionBK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release . A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia . This has major implications on other physiological processes in tissues other than the brain.
Related Pathway

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WB Image
Western blot analysis of BK Beta2 in a human cell line mix using a 1:1000 dilution of the antibody

 

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