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Anti-KCNMB2 TRUEMAB Antibody S53-32
Also for KCNMB2 (NM_181361)
|Fusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 ( |
|Human, Mouse, Rat
||WB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
|PBS pH7.4, 50% glycerol, 0.09% sodium azide |
|Protein G Purified
|Detects endogenous and exogenous hsp22 in monomeric, dimeric and tetrameric forms in WB. Does not cross react with alpha crystallin.
|Homo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2), transcript variant 1|
|BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release . A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia . This has major implications on other physiological processes in tissues other than the brain.|
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Western blot analysis of BK Beta2 in a human cell line mix using a 1:1000 dilution of the antibody