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Home Antibody All anti-KCNMA1 antibodies

Anti-KCNMA1 Antibody S6-60

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326487
  • Mouse Monoclonal Anti-Slo1 Antibody
100µg $325 3-7 Days
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WB(1)
IHC(1)
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Also for KCNMA1 (NM_001014797)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenFusion protein amino acids 690-1196 (cytoplasmic C-terminus) of mouse Slo1
Clone NameS6-60 IsotypeIgG2a
Species ReactivityMouse, Human, Rat, Zebrafish Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~110-130kDa. Epitope mapped within amino acids 690-715.

Reference Data

Target NameHomo sapiens potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (KCNMA1), transcript variant 1
Alternative NamebA205K10.1; BKTM; KCa1.1; MaxiK; mSLO1; SAKCA; SLO; SLO-ALPHA; SLO1
Database LinkNP_001014797
FunctionThe Slo1 channel is a novel potassium channel that is regulated by both Ca2+ and voltage. It is a homolog to the pH and voltage-regulated Slo3 channel. Four distinct subunits composing the KCNMB family are known to regulate the function and expression of Slo1 channels . Slo1 has been shown to be involved in neurotransmitter release and etheanol response. It has been reported that SLO1 also has a critical role is muscles- the inactivation of the slo-1 gene in muscles leased to phenotypes similar to those cause by mutations of the dystrophin homologue dys-1 .
Related Pathway

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WB Image
Western blot analysis of Slo1 on rat brain membrane tissues using a 1:1000 dilution of the antibody
IHC Image
IHC analysis of Slo using the antibody

 

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