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Anti-KCNMA1 Antibody S6-60
Also for KCNMA1 (NM_001014797)
|Fusion protein amino acids 690-1196 (cytoplasmic C-terminus) of mouse Slo1 |
|Mouse, Human, Rat, Zebrafish
||WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
|PBS pH7.4, 50% glycerol, 0.09% sodium azide |
|Protein G Purified
|Detects ~110-130kDa. Epitope mapped within amino acids 690-715.
|Homo sapiens potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (KCNMA1), transcript variant 1|
|bA205K10.1; BKTM; KCa1.1; MaxiK; mSLO1; SAKCA; SLO; SLO-ALPHA; SLO1|
|The Slo1 channel is a novel potassium channel that is regulated by both Ca2+ and voltage. It is a homolog to the pH and voltage-regulated Slo3 channel. Four distinct subunits composing the KCNMB family are known to regulate the function and expression of Slo1 channels . Slo1 has been shown to be involved in neurotransmitter release and etheanol response. It has been reported that SLO1 also has a critical role is muscles- the inactivation of the slo-1 gene in muscles leased to phenotypes similar to those cause by mutations of the dystrophin homologue dys-1 .|
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Western blot analysis of Slo1 on rat brain membrane tissues using a 1:1000 dilution of the antibody
IHC analysis of Slo using the antibody