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Anti-BSN Antibody


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SKU Description Amount Price Availability*  
TA326448 Rabbit Polyclonal Anti-Bassoon Antibody 100µg $325 3-7 Days
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OriGene Data

ImmunogenNM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
Clone Name Isotype
Species ReactivityHuman, Mouse, Rat. Not yet tested on other species. Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~420kDa, corresponding to the molecular mass of Bassoon. Multiple isoforms can be detected.

Reference Data

Target Namebassoon presynaptic cytomatrix protein
Alternative NameZNF231
Database LinkNP_003449
Entrez Gene 8927 Human
Entrez Gene 12217 Mouse
Entrez Gene 29138 Rat
FunctionBassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntingtin, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to colocalize with GABA (A) and glutamate (GluR1) receptors.
Related Pathway

* Availability is in business days
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WB Image
Western blot analysis of Bassoon in mouse and rat brain lysate using a 1:1000 dilution of the antibody

IHC Image
Bassoon, BTX and overlay. Neuromuscular junction whole muscle samples from adult mouse with 1:400 dilution of the antibody, secondary (Alexa 488 goat anti-rabbit). It shows bright staining of the NMJ very seltectively and brightly.


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