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Home Antibody All anti-TLR4 antibodies

Anti-TLR4 Antibody N/A

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326405
  • Rabbit polyclonal TLR4 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC408575) , 20ug
100µg $325 3-7 Days
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WB(1)
IHC(1)
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Also for TLR4 (NM_138554)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDeveloped against a synthetic peptide corresponding to amino acids 420-435 of human TLR4.
Clone NameN/A IsotypeN/A
Species ReactivityHuman, Mouse Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1-3ug/ml, IHC: 1:50
BufferPBS, 0.05% BSA, 0.05% sodium azide
Purification Affinity Purified
Note Detects ~75-80kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag).

Reference Data

Target NameHomo sapiens toll-like receptor 4 (TLR4), transcript variant 1
Alternative NameARMD10; CD284; TLR-4; TOLL
Database LinkNP_612564
FunctionThe Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules . The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition . Ten human homologs of TLRs (TLR1-10) have been described . Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediatiors of LPS signaling . The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90kDa .
Related Pathway
Toll-like receptor signaling pathway

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WB Image
Western blot analysis of TLR4 using a 1:1000 dilution of the antibody
IHC Image
IHC analysis of TLR4 using the antibody

 

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