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Home Antibody All anti-KCNMB3 antibodies

Anti-KCNMB3 Antibody S40B-18

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326402
  • Mouse monoclonal BK Beta3a Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC406784) , 20ug
100µg 325 3-7 Days
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WB(1)
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Also for KCNMB3 (NM_171828)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenFusion protein amino acids 1-49 (unique N-terminus) of mouse BKBeta3a
Clone NameS40B-18 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~32 kDa. No cross-reactivity against BKBeta1, BKBeta1, BKBeta3b or BKBeta4.

Reference Data

Target NameHomo sapiens potassium large conductance calcium-activated channel, subfamily M beta member 3 (KCNMB3), transcript variant 1
Alternative NameBKBETA3; HBETA3; KCNMB2; KCNMBL; SLOBETA3
Database LinkNP_741979
FunctionBK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release . A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia . This has major implications on other physiological processes in tissues other than the brain.
Related Pathway

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WB Image
Western blot analysis of BKBeta3a in rat brain membrane lysates using a 1:1000 dilution of the antibody

 

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