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Home Antibody All anti-HIF1AN antibodies

Anti-HIF1AN Antibody FIH 162c

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA326397 Mouse monoclonal FIH Antibody 100µg $325 3-7 Days
LC402628 HIF1AN HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for HIF1AN (NM_017902)
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OriGene Data

ImmunogenFull length human FIH expressed in E.coli BL21 (DE3) cells
Clone NameFIH 162c IsotypeIgG1
Species ReactivityHuman Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~45kDa (human) proteins, corresponding to the molecular mass of FIH on SDS PAGE immunoblots

Reference Data

Target Namehypoxia inducible factor 1 alpha subunit inhibitor
Alternative NameFIH1
Database LinkNP_060372
Entrez Gene 55662 Human
FunctionFIH, Factor inhibiting HIF1 (hypoxia-inducible factor), is an asparaginyl hydroxylase. FIH in conjunction with VHL represses HIF-1 transcriptional activity by disrupting the interaction of HIF-1 with the transcriptional coactivators CBP/p300, and by recruiting histone deacetylases. FIH activity is inhibited during hypoxia . Recent studies show that low nuclear expression of FIH is a strong independent prognostic factor for a poor overall survival in clear cell renal cell cancinoma .
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
Western blot analysis of FIH in a human cell line mix, using a 1:1000 dilution of the antibody
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IHC Image
FIH visualized using the antibody
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